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"A Trial Comparing the Safety and Efficacy of Semaglutide Once Weekly in Monotherapy or in Combination With One OAD in Japanese Subjects With Type 2 Diabetes (SUSTAIN)"

Jensen L, Helleberg H, Roffel A, van Lier JJ, Bjrnsdottir I, Pedersen PJ, Rowe E, Derving Karsbl J, Pedersen ML

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[13] A cardiovascular-outcomes trial of this size matters especially for a glucagon-containing molecule, because the glucagon axiss effects on heart rate and glucose make long-term cardiovascular safety a first-order question rather than an afterthought